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This volume focuses on stem cell research and disease modeling in non-murine species. The book is divided into three parts: Stem Cells for Pre-Clinical Models, Stem Cells in Non-Conventional Species, and Stem Cell Banking for the Future. The first section presents an overview of the different pre-clinical stem cell models recently created in animal species, including the porcine model for heart failure, iPSC in large animal species, Duchenne muscular dystrophy and canine embryo-derived stem cells and modeling for human diseases. This section also discusses the potential advantages and...

This Brief offers a concise, handy overview of the main concepts related to Embryology, revisited through the novel concepts that are applied daily in stem cell research and cell therapy oriented investigations. It is based on three main areas:

-The process involved in female gamete differentiation and maturation. The main aspects related to cell biology will be covered and an overview of the epigenetic regulation of gametogenesis will be presented.

-Early stages of embryo development with a careful analysis of the regulatory mechanisms driving cleavage, polarization and...