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The marine environment is a habitat for many unique microorganisms, which produce biologically active compounds ("bioactives") to adapt to particular environmental conditions. Actinomycetes are a family of bacteria that produce over two thirds of the clinically useful antibiotics of natural origin. The present study deals with production and extraction of antimicrobial metabolites from haloalkaliphilic actinomycetes from the Gulf of Khambhat situated in the Bhavnagar District of the Gujarat. Out of 40 isolates, isolate GhM-HA-6 was found to secrete potential antimicrobial metabolites against...

Enzymes are the bioactive compounds that have focused attention. The demand for microbial enzymes in industrial fields is increasing day by day due to their applications in clean and cost effective biotechnological processes. A halo-tolerant and alkaliphilic bacterium, Kh-30-2, was isolated from saline soil of the desert of Kutch, Gujarat. The organism secreted a range of extracellular enzymes including protease, cellulase and lipase with 10% NaCl and pH 9. It secreted alkaline protease optimally with 0.5 % w/v, peptone and yeast extract. The enzyme was partially purified by ammonium sulphate...

Research on cellulase has progressed very rapidly over the last five decades. Now a day, majority of commercial cellulases are being produced by fungi such as, Trichoderma. However halophilic fungi can be a valuable resource for the same. The present study deals with the extracellular cellulases from Halophilic fungi isolated from the Great Rann of Kutch, India. The isolates, designated as B10-1 and D10-2 were having mycelia structure similar to Aspergillus spp. and grew optimally with 10% w/v NaCl. B10-1 and D10-2 grew optimally at pH 6 with slow growth at higher pH. In case of B10-1 and...

Actinomycetes have provided important bioactive compounds of high commercial value and continue to be routinely screened for new bioactive substances. There is an alarming scarcity of new antibiotics currently under development in the pharmaceutical industry. The present study highlights the isolation and characterization of haloalkaliphilic actinomycetes with respect to their antimicrobial potential. A total of 14 halophilic, alkaliphilic and haloalkaliphilic actinomycete isolates were isolated from the saline soil samples collected from the saline desert of Kutch under varied conditions of...