1. Introduction to chemometrics 2. Introduction to chromatography 3. Chromatographic system optimisation (efficiency, time, and peak capacity optimisation) 4. Chromatographic selectivity optimisation (retention time optimisation) 5. Signal pre-processing in chromatography 6. Peak detection and quantitification of resolved peak 7. Peak fitting with single-channel detection 8. Peak resolution for multi-channel detection 9. Chemometrics and two-dimensional chromatography with single channel detection 10. Chemometrics and two-dimensional chromatography and multichannel detection 11. Fingerprinting and pattern recognition in chromatography 12. Appendix