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wyszukanych pozycji: 9
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Fundamentals of Medical Pharmacology
ISBN: 9783659433276 / Angielski / Miękka / 2015 / 568 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. The medicinal/ organic chemist may create the candidate compound (sometimes referred to as a new chemical entity, NCE), it is the pharmacologist who is responsible for testing it for pharmacological activity. Ultimately will lead to the discovery of novel drug targets for therapeutic intervention in diseases where distal steps in signal transduction have gone awry. Pharmacology studies the effects of drugs and how they exert their effects. Aspirin can reduce inflammation, pain and fever inhibit the action of a human cell membrane enzyme known as cyclooxygenase, which is responsible for the...
The medicinal/ organic chemist may create the candidate compound (sometimes referred to as a new chemical entity, NCE), it is the pharmacologist who i...
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cena:
475,83 zł |
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Ibd: Biomarkers of UCEIS
ISBN: 9783659814655 / Angielski / Miękka / 2015 / 80 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. The characteristic pathologic feature of UC is infiltration of the intestine by mononuclear cells, predominantly lymphocytes. Current research is directed to Vitamin D and its role in the disease activity in patients with IBD. The aim of the present study is to investigate the serum level of vitamin D and other biomarkers e.g. adhesion molecules in patients diagnosed with UC and determining the statistical correlation of these molecules with each other and ultimately with endoscopic severity of UC.
The characteristic pathologic feature of UC is infiltration of the intestine by mononuclear cells, predominantly lymphocytes. Current research is dire...
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cena:
180,99 zł |
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Dmso: A Double Edged Sword
ISBN: 9783659796418 / Angielski / Miękka / 2015 / 68 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. DMSO is also widely utilized in the storage of human and animal cell lines and bacteriophage, as a cryoprotective agent.Previous studies reported that DMSO reduces inflammation by several mechanisms. It is an antioxidant, a scavenger of the free radicals that gather at the site of injury. The present work aims at investigation of the potential anti-inflammatory activity of DMSO in adjuvant-induced arthritis in rats. Moreover, histopathology for the scarified joints after administration of oral DMSO to adjuvant arthritic rats was examined.
DMSO is also widely utilized in the storage of human and animal cell lines and bacteriophage, as a cryoprotective agent.Previous studies reported that...
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cena:
180,99 zł |
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Ibd: studying correlation between some biomarkers
ISBN: 9783659608957 / Angielski / Miękka / 2015 / 64 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. Arginase (AR)enzyme is implicated in many studies in pathogenesis of IBD.E-selectin , an adhesion molecule, plays an important role in migration of leucocytes into the colonic mucosa.Many studies have gone on to suggest that vitamin D deficiency is a contributing factor in the pathogenesis of IBD.The aim of the present work is to investigate the possible correlation between serum levels of vitamin D, the adhesion molecule E-selectin and the enzyme arginase in UC diagnosed cases.
Arginase (AR)enzyme is implicated in many studies in pathogenesis of IBD.E-selectin , an adhesion molecule, plays an important role in migration of le...
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cena:
180,99 zł |
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Snp: A Potential Immunomodulator
ISBN: 9783659801723 / Angielski / Miękka / 2015 / 152 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. SNP,a nitric oxide (NO) donor is a common medication used to affect peripheral vasodilation in arterioles and venules. SNP is often administered intravenously to patients who are experiencing a hypertensive emergency. Interesting studies have implicated that NO is a double edged soword. It has been reported that relatively low concentration of NO plays a defensive role in the immune system while higher concentration causes numerous pathological processes including inflammation.
SNP,a nitric oxide (NO) donor is a common medication used to affect peripheral vasodilation in arterioles and venules. SNP is often administered intra...
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cena:
280,78 zł |
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Cardiovascular And Neuromodulatory Effects Of Purine P1 Agonists
ISBN: 9783659812705 / Angielski / Miękka / 2015 / 108 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. The present work investigates the effect of rats pretreatment with the purinergic agonists ADO, 2-CADO, CPA and CPCA on the forebrain levels of the neurotransmitters glutamate and GABA in rats after PTZ challenge. In a trial to correlates cardiovascular effects with the neuromodulatory effects of the aforementioned agonists , the CVS effects of these agonists in addition to determination of their TD50 before and after PTZ- induced seizures were also investigated.
The present work investigates the effect of rats pretreatment with the purinergic agonists ADO, 2-CADO, CPA and CPCA on the forebrain levels of the ne...
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cena:
249,03 zł |
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Effect of vitamin D deficiency on ICAM in UC
ISBN: 9783659815195 / Angielski / Miękka / 2015 / 56 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. Many studies have gone on to suggest that vitamin D deficiency is a contributing factor in the pathogenesis of ulcerative colitis (UC). Adhesion molecules e.g. intracellular adhesion molecule (ICAM), represent a promising therapeutic targets for human inflammatory diseases, including UC. The aim of the present work is to investigate the possible correlation between serum levels of vitamin D, the adhesion molecule ICAM in diagnosed cases of UC.
Many studies have gone on to suggest that vitamin D deficiency is a contributing factor in the pathogenesis of ulcerative colitis (UC). Adhesion molec...
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cena:
180,99 zł |
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Adenosine Versus Theophylline Toxicity
ISBN: 9783659803123 / Angielski / Miękka / 2015 / 200 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. |
cena:
326,14 zł |
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NO modulation and potential antiarthritic effect of rolipram
ISBN: 9783659791963 / Angielski / Miękka / 2015 / 132 str. Termin realizacji zamówienia: ok. 10-14 dni roboczych. Rolipram is a phosphodiesterase-4 (PDE 4) inhibitor. It is being researched as a possible alternative to current antidepressants (Washtel, 1983; Bobon et al., 1988). Recent studies show that rolipram may have antipsychotic effects (Maxwell et al.,2004; Kanes et al., 2006).There is a conflicting data about the role of nitric oxide (NO) in arthritic diseases. In the present work, we examined whether the suppression of NO production by L- NG - monomethyl arginine (L-NMMA), a non-selective NOS inhibitor or addition of exogenous NO by administration of sodium nitroprusside (SNP) can modify the...
Rolipram is a phosphodiesterase-4 (PDE 4) inhibitor. It is being researched as a possible alternative to current antidepressants (Washtel, 1983; Bobon...
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cena:
280,78 zł |
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