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This text contains the refresher course lectures of the 1999 meeting, and provides a review of the state of the art in anesthesia clinical pharmacology. The authors of the individual chapters are recognized experts in the pharmacology of perioperative medicine. The book features sections on pharmacology concepts, drug delivery techniques, the latest drugs, and novel thinking about older drugs. It also addresses several areas that have emerged as very hot clinical and research topics, including depth of anesthesia monitoring technology and anesthesia drug interactions.