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Bacterial plaque has been established as the primary etiologic factor for the initiation of periodontal disease. However, it has been shown that without a susceptible host the periodontal pathogens are butnot sufficient for disease to occur. Hence, systemic conditions of the host must be understood as they may affect disease prevalence progression and severity. These hormones have been suggested as important modifying factors that may influence the pathogenesis of periodontal diseases. The homeostasis of the periodontium involves complex multifactorial relationships in which the endocrine...