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Chronic Suppurative Otitis Media (CSOM) is a chronic inflammation of the middle ear and mastoid cavity, which presents with a perforated tympanic membrane, through which microorganisms can enter into the middle ear. Infection can spread from the middle ear to vital structures such as the mastoid, facial nerve, labyrinth, lateral sinus, meninges, and brain. It is a common cause of hearing impairment and can occasionally lead to fatal intracranial infection.Prevalence surveys estimate that the global burden of illness from CSOM may involve 65 to 330 million individuals with draining ears....