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Ever since it was published in 1978, the picture-book presentation of Robert Frost's poem "Stopping by Woods on a Snowy Evening" has been an enduring favorite. For this special edition with a new design, trim size, and three new spreads, Susan Jeffers has added more detail and subtle color to her sweeping backgrounds of frosty New England scenes. There are more animals to find among the trees, and the kindly figure with his "promises to keep" exudes warmth as he stops to appreciate the quiet delights of winter. The handsome new vellum jacket will attract new and old fans as it evokes a...

These are structurally related to the beta CAs, but have a mechanism more similar to the alpha CAs.

The study of carbonic anhydrase has spanned multiple generations of scientists. Carbonic anhydrase was first discovered in 1932 by Meldrum and Roughton. Inhibition by sulfanilamide was shown in 1940 by Mann and Keilin. Even Hans Krebs contributed to early studies with a paper in 1948 showing the relationship of 25 different sulfonamides to CA inhibition. It was he who pointed out the importance of both the charged and uncharged character of these compounds for physiological experiments. The field of study that focuses on carbonic anhydrase (CA) has exploded in recent years with the...