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Chemolithotrophy is oxidations of inorganic substances fulfill the nutritional requirements of the organisms. Genomic studies revealed soxSRT and soxVWXYZABCD which governs chemolithotrophy. Four proteins, SoxXA, SoxYZ, SoxB and SoxCD, forms multienzyme complex system (TOMES) to carry out oxidation of thiosulfate. Sequence analysis of sox operon showed various promoters and regulatory genes soxSRT, codes for thioredoxin, transcriptional regulator and a transporter protein. Little was known about the regulational control of the sox gene expression that motivated to investigate the gene...