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Starting with the introduction, readers are shown the dire need for prevention and the peculiarities of preventing a problem that is typically recurrent. In the second section, risk factors and mechanisms are examined that provide a unique and in-depth understanding of how disability develops and thereby how it might be prevented. Chapters are dedicated to major risk factors such as stress, ergonomics and fear-avoidance as well as to the overriding question of why acute pain sometimes develops into a chronic problem. The major challenge facing the field today is developing effective...

A comprehensive review of the current state of thinking and research in relation to the management of the psychological aspects of pain. Written in a style and at a level which is relevant and accessible to the practising clinician and also to students. Addresses the common clinical problems relating to the psychological aspects of pain management and gives practical guidance based on the latest research as to how those problems should be dealt with. Includes an appendix which may be used as a session manual by therapists using cognitive-behavioural therapy with groups for early intervention...

Presents the Therapeutic Potential for Caspase Inhibitors: Present and Future

Caspases represent one of the most specific protease families described to date. These extremely important enzymes are crucial to the destruction of aberrant cells the body s self-protection mechanism for warding off the growth of abnormal cells, many of which can promote cancer. Design of Caspase Inhibitors as Potential Clinical Agents introduces cutting-edge evidence regarding caspases role in pro-inflammatory responses. New research now shows that the inhibition of...

This resource comprises a collection of papers from participants at the IMCS Workshop on Computational and Geometric Aspects of Modern Algebra, held at Heriot-Watt University in 1998. Written by leading researchers, the articles cover a wide range of topics in the vibrant areas of word problems in algebra and geometric group theory. This book represents a timely record of recent work and provides an indication of the key areas of future development.