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Offers powerful PCR-based protocols and assays in actual use or potential use in clinical medicine and commercial biology. The main focus of the book is on the commercial applications of PCR, as opposed to basic research uses. Topics covered include: the measurement of hormone levels using PCR; transcription factor isolation; detection of viruses using PCR; detection of tumour contamination of stem cells; and evaluation of grafts for tumour cells.

A renowned orator and writer, Lincoln believed that he must speak plainly so that every American, regardless of their level of education or literacy, would understand the complicated issues affecting the country during his presidency. He overcame a very humble childhood to become our nation's sixteenth president and a trailblazer in the fight to abolish slavery. In addition to the accomplishments of his lifetime, it is Lincoln's simple but elegant words--in everything from the Emancipation Proclamation to compassionate and often humorous letters to family and friends--that are his legacy....

The invention of the polymerase chain reaction (PCR) eventually earned Kary B. Mullis half of the 1993 Nobel Prize for Chemistry (1-4). However, for several years, issues of quality control and reproducibility interfered with attempts at commercial or clinical application of PCR. More recently, persistent work and numerous methodological inno- tions and refinements have resulted in the establishment of PCR as a routine, sensitive, and specific detection method in hospital and agricultural labora- ries. This transformation of PCR from an experimental research technique to an established...