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Stephen P. Ethier and a panel of leading investigators comprehensively analyze the cellular, molecular, and endocrine factors in the development of cancers of the breast, prostate, endometrium, and ovary. Concentrating on defining the most important unresolved issues in the field, the authors review how steroid hormones function to regulate normal mammary gland homeostasis in humans, with particular emphasis on the roles of estrogen, progesterone, and growth factors. Comprehensive and up-to-date, Endocrine Oncology offers both basic and clinical researchers not only the latest molecular and...

Stephen P. Ethier and a panel of leading investigators comprehensively analyze the cellular, molecular, and endocrine factors in the development of cancers of the breast, prostate, endometrium, and ovary. Concentrating on defining the most important unresolved issues in the field, the authors review how steroid hormones function to regulate normal mammary gland homeostasis in humans, with particular emphasis on the roles of estrogen, progesterone, and growth factors. Comprehensive and up-to-date, Endocrine Oncology offers both basic and clinical researchers not only the latest molecular and...

Tremendous progress has been made in the war on cancer, leading to improvements in cancer prevention, detection, and treatment. Together, these advances have resulted in decreasing incidences and a steadily declining death rate from cancer. However, for patients who develop stage IV cancer, cancer that has spread to distant organs, their prognosis remains grim. Conventional chemotherapy is limited in its ability to successfully eradicate metastatic disease. Therefore, new modalities and approaches are desperately needed if we are to make progress toward conquering this last mountaintop of...