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Volumes 7 and 8 of the Handbook were published in 1977. In Volume 7 methods for studying unconditioned and conditioned behavior were reviewed. Attention was given to both ethological methods and operant conditioning techniques as applied to some selected aspects of behavior. Genetic, developmental, and environmental factors influencing behavior were also discussed. In Volume 8, neurotransmitter systems, and in par ticular brain circuits, were discussed in relation to behavior and to the effects of psychoactive drugs on behavior. The coverage was not exhaus tive because of space limitations....

"Psychopharmacology of the Aging Nervous System" was selected as the topic for Volume 20 of the Handbook of PsychopharmacoloffY. Senile dementia is now widely recognized as a medical and social problem likely to reach epidemic proportions by the turn of the century. By that time it is esti mated that almost 20% of the population in most developed countries will be over the age of 65 and at a conservative estimate 1 in 10 of them will suffer from a dementing illness. Many symposia have appeared over the last few years describing the neuropathological and neurochemical deficiencies in...

Volume 18 of the Handbook of Psychopharmacology represents the first of a series of volumes intended to bring earlier sections of the work up to date. Volumes 7, 8, and 9, published in 1977 and 1978, dealt with principles of behavior, drugs and neurotransmitters, and neuroanatomy. In subsequent volumes dedicated to these issues, a mixture of topics will be covered in a given volume, covering both advances in basic knowledge in these three areas of the subject and reviews of theoretical and meth- odological issues deemed to be of particular relevance at present. L. L. . S. D. . S. H. S. vii...