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A better understanding of the viability and virulence of putative endodontic pathogens may help explain the mechanism, different clinical presentations of endodontic infections and inturn contribute to identification of therapeutic targets. This study attempts to provide an insight into the diverse range of microflora that infect the root canal system. Their virulence factors and host response are discussed along with the mechanism of establishment of pulp and periradicular lesions. The current advancements in molecular methods of isolation and detection of previously unidentified micro...

Tooth resorption is a perplexing problem for all dental practitioners. The etiologic factors are vague, diagnoses are educated guesses, and often the chosen treatment does not prevent the rapid disappearance of the calcified dental tissues. Although the occurrence of resorption cannot always be predicted, resorption can be identified radiographically. However, even this diagnostic tool has limitations, especially with respect to resorption on the buccal and lingual surfaces. The diagnostic dilemma is further complicated by the need to differentiate between internal from external resorption....