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Chemotherapy induced nausea and vomiting (CINV) is a serious distress for cancer patients, who have to receive chemotherapy for their treatment. Ondansetron HCl is an effective antiemetic drug which is used to prevent CINV. But this drug is commercially available in the form of tablet and injection, which causes its hepatic "first pass" metabolism or rapid clearance from the body, respectively. Hence, the need to formulate such a dosage form of this drug that will not only enhance its bioavailability but also provide adequate patient compliance. This book focuses on development and in vitro...

Tinidazole is mainly used in the treatment of colon specific diseases. The present study deals with preparation and evaluation of zinc pectin microbeads of tinidazole as a colon specific drug delivery system. This type of formulation helps to release the drug in a sustained manner to the colon which can quite effectively control the diseased conditions and provide proper therapeutic efficacy of the drug to the patient.