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It is a chronic progressive degenerative disorder of the extrapyramidal system caused by loss of dopaminergic neurons in the substantianigra and characterized by tremors, rigidity, bradykinesia, and disturbance of gait and posture. The neuropsychiatric symptoms of PD may include depression, psychosis, apathy, impulse control disorders that are linked with the poor quality of life due to the progression of the disease. Despite this, cognitive impairment in PD is of great significance in terms of therapeutic approaches in order to deal with motor deficits of the disorder. Multiple studies have...

Nanoparticles hold tremendous potential as an effective drug delivery system. In this overview we discussed recent developments in nanotechnology for drug delivery. To overcome the problems of gene and drug delivery, nanotechnology has gained interest in recent years. Nanosystems with different compositions and biological properties have been extensively investigated for drug and gene delivery applications. To achieve efficient drug delivery it is important to understand the interactions of nanomaterials with the biological environment, targeting cell-surface receptors, drug release, multiple...