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Prodigiosin was isolated from fermented broth of isolated marine bacterial strain Vibrio sp. The compound was characterized, and evaluated for its antimicrobial properties. The isolated strain was molecularly identified based on 16S rRNA based phylogenetic analysis. This molecular analysis data suggested that this strain is closely related to Vibrio sp. The extract was purified and characterized by spectral data using NMR and MASS and confirmed as analogue 2,2'- 3-methoxy-1'amyl-5'-methyl-4-(1''-pyrryl)] Prodigiosin structure. Prodigiosin exhibited antioxidant and broad spectrum antimicrobial...

Current research in drug discovery from medicinal plants involves an ultifaceted approach combining botanical, phytochemical, biological, and molecular techniques. Medicinal plant drug discovery continues to provide new and important leads against various pharmacological targets. The plant extract were screened for antimicrobial activity against different species by the agar well diffusion assay. The aqueous extracts of Catharanthus roseus were found active against both Gram-positive and Gram-negative bacteria. The antiangiogenic efficacy of Catharanthus roseus leaf extract was examined in...