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A series of seven nateglinide analogues were synthesized successfully using 4-isopropyl cyclohexyl carboxylic acid (trans acid) as starting material, react with thionyl chloride and formed trans-4-isopropyl cyclohexane carbonyl chloride (trans acid chloride) as an intermediate which further reacted with D-phenylalanine to yield nateglinide. The derivatives were synthesized by reacting nateglinide and ethylchloroformate, and formed an unstable mix anhydride compound, which further react with primary and secondary amines to yield the nateglinide derivatives. All these molecules were...

An electrocardiogram (ECG) is a vital diagnostic tool used to measure the electrical activity of the heart. It provides a visual representation of the heart's rhythm, rate, and other important parameters, allowing doctors to diagnose and monitor a wide range of heart conditions.ECG interpretation can be a daunting task, particularly for healthcare professionals who lack formal training in cardiology. However, with the right approach, anyone can learn to interpret ECGs accurately and efficiently.One common pitfall when interpreting ECGs is overcomplicating the analysis. It's easy to get lost...