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There is an urgent need to develop effective strategies to combat the emerging global epidemic of Metabolic Syndrome, especially in resource crunched developing countries like India. Further studies are to be conducted towards a truly universal criterion of MetS with potential ethnic differences, and effect of genetic and perinatal factors on the latter. There are many actions of genes activated by PPAR- agonists, only some of which are currently known. PPAR- indeed has many faces. It is the master regulator of adipocyte differentiation yet promotes insulin sensitivity. Further research on...

The treatment of gram-negative bacteremia is increasingly complicated by the occurrence of multidrug resistant gram-negative bacilli strains. Normally susceptible bacteria may become resistant to antimicrobial agents through mutation and selection or acquisition from other bacteria of genetic information that encodes resistance. Enterobacterial resistance to third-generation cephalosporins is typically caused by production of extended-spectrum beta-lactamases . CTX-Ms are one of the means of antibiotic resistant marker transfer among members of Enterobacteriaceae. Continous surveillance will...