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Nitric oxide research has emerged as one of the most important new areas in bone and joint diseases. This book is the first to bring together current knowledge on the actions of nitric oxide and its role in such common diseases as arthritis and osteoporosis. The volume introduces the basic biology and biochemistry of nitric oxide, the immune response, and bone biology. While doing so, it reviews in depth the facts we know today and the future promise of this exciting area of research. Throughout the book, the authors emphasize potential new treatments that exploit our understanding of the...

The rational expectations revolution and other developments in economics (notably game theory) have fundamentally altered the application of optimal control theory to economic forecasting and planning. In particular, they have shown that economic systems cannot be modeled simplistically on physical systems. However, as the authors show, these developments have greatly enhanced our understanding of how an economy functions, and now make it possible for optimal control theory to be applied much more effectively to economic modeling and planning.