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In this proof of principle study, automated fluorescence Toponome Imaging System (TIS) was applied to find protein network structures distinguishing cancer tissue from normal colon tissue, taken from the same patient. Cancer specimen and corresponding normal tissue were harvested at colectomy from a single patient and prepared for TIS using a battery of different antibodies, including a number of putative stem cell markers. Expression of multiple protein clusters was determined and Combinatorial Molecular Phenotypes (CMPs) were analysed, using specific image-analysis tools. By sub-cellular...

This book focuses on the most recent developments in bioremediation techniques, exploring how microorganisms can break down different pollutants and the future potential of bioremediation to reduce global pollution levels. It examines the impact of various emerging pollutants on the environment and the health of living organisms while highlighting recent advancements in bioremediation methods needed to degrade these pollutants. Addressing both inorganic and organic compounds from industrial and anthropogenic activities, including personal care products, endocrine disruptors, and...