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Cancer is high proliferation of cells due to abnormalities in cell division and DNA replication. Breast cancer is most common malignancy of women with 45-80% response rate. However, recurrence is most common and most of the patients do not develop a satisfactory immunological antitumour response due to several mechanism, T-cells dysfunction. It is about 1% in men. In present study, we tried to investigate the role of T-cells and DNA content analysis as prognostic marker in breast cancer patients compared to normal healthy individuals using Flowctometry and Confocal Laser Scanning Microcopy....

Cancer is abnormal division of cells with the ability to invade other tissues. Cancer may be of more than 100 types depending on the origin of organ or cell types in which they start. Breast cancer begins in the cells of the lobule or ducts or in the stromal tissues .Genetic abnormality is also one of the main cause of breast cancer. Whereas prostrate cancer occurs due to mutation and may spread to other parts of body. Immunohistochemical and Immnofluorescence study of COX-2 expression in 29 cancer patient samples was performed. Cyclooxygenase (COX) is an angiogenic factor i.e., strongly...

The brain cells called neurons are meant to divide rapidly. Brain cancer starts in just one cell when a division starts dividing in an uncontrolled manner. As the cell makes more copies of itself, it grows to form a tumor, may be Benign or Malignant tumors. Immunohistochemical study of tissue Transglutaminase (tTG) in 22 brain tumor samples was performed. tTG expression was observed visually in endothelial and tumor cells. In most of the cases, the tTG expression was observed in endothelial cells but in few cases tTG expression was also observed in tumor cells along with endothelial cells....