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The aim of the work is to evaluate the transdermal potential of novel vesicular carrier, ethosomes, bearing aceclofenac, Non-steroidal anti-inflammatory drugs having limited transdermal permeation. Aceclofenac loaded ethosomal carriers were prepared, optimized and characterized for vesicular shape and surface morphology, scanning electronic microscopy, vesicular size, entrapment efficiency, stability, in- vitro release study.The formulation having 3% phospholipids content and 40% ethanol showing the grater entrapment and optimal average vesicle size of formulation was determine by Malvern...

The present book contains the simple, fast and precise stability indicating method for the extended release formulation of Diclofenac sodium using high pressure liquid chromatography (HPLC).It contains the fundamental concepts to the analytical chemistry along with the in depth knowledge of HPLC. The objective of this book was to provide the basic concepts of the analysis by HPLC to the pharmacy fraternity.