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The presence of >C=N- group is of great importance by considering the fact that it can be transformed into various heterocyclic ring compounds. The availability of the presence and significant biological properties of the members known so far prompted the authors to extend moieties like 2-azetidinones. Various Schiff bases Schiff based of 4-amino-N-(4-(2,4-dichlorophenyl)-6-(6-methylnaphthalen-2-yl)pyrimidin-2-yl)benzenesulfonamide (6a-h) mentioned in chapter-2 on heterocyclization reaction with chloroacetyl chloride yield the biologically active 2-azetidinones (beta-lactams).

Schiff bases are the compounds containing azomethine group (-HC=N-) formed by condensation of a primary amine with an active carbonyl compound. Sulfonamide derivatives have been subjected through studies where a wide diversity of those derivatives have been prepared and used in various biological and pharmacological fields. Schiff bases are the among the most studies sulfonamide derivatives which have been used for several biological application. These type of derivatives are very important because of their varied structure and biological activities. In continuation of our work on...