Wyniki wyszukiwania:

Post-translational phosphorylation is one of the most common protein modifications that occur in animal cells. The vast majority of phosphorylation occurs as a mechanism of acute and reversible regulation of protein function. Studies of mammalian cells metabolically labeled with p32 orthophosphate suggest that as many as one-third of all cellular proteins are covalently modified by protein phosphorylation. Covalent attachment of a phosphate group to an amino acid side chain of a protein can cause a structural change, for example, by attracting a cluster of positively charged side chains. Such...

Bladder cancer is an important public health problem in Egypt which constitutes 30% of all cancers. Cytology could serve as an excellent test for screening but it is of lower sensitivity. Early diagnosis is critical for maximizing the cure rate of bladder cancer patients, so many urine-based tumor markers have been developed for use in detecting and monitoring bladder cancers. Hypermethylation of CpG islands in the promoter regions of RAR 2 tumor suppressor gene is a major event in the origin of many cancers. In the present study detection of methylated RAR 2 gene was done in the urine of 183...