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Diabetes mellitus is one of the most serious healthcare concerns of 21st century and is characterized by deficiency or inaction of insulin. Exogenous insulin is quite helpful in ameliorating these conditions. But it fails to produce a well-controlled glycemic condition in association with variable dietary intake and physical activity. Episodes of severe hypoglycemia leading to deleterious cerebral impact are common during insulin administration. Thus there is a need to develop antidiabetic drugs that are effective, safe, produce a well-controlled normoglycemia and prevent the long-term...