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Dental trauma in young children can lead to pulp devitalization of immature permanent teeth and cessation of root development. Endodontic treatment of immature necrotic permanent teeth is challenging. The divergent radicular morphology, accompanied by lack of apical constriction and thin dentin, can lead to inadequate root canal disinfection and overfilling with a high risk of extruded gutta-percha. Regenerative endodontics has gained enormous attention over recent years. Proposed by Nygaard-Ostby in 1961, inducing bleeding through over-instrumentation introduces stem cells from the...