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This work describe new electrometric methods for the determination of the antidepressant drug, sertraline hydrochloride. membrane, coated wire and chemically modified carbon paste sensors sensitive for sertraline hydrochloride were constructed. They were constructed and fully characterized. Each sensor was applied to the potentiometric determination of the drug cation in the pure form and pharmaceutical preparations. Conductimetric measurement for the solubility product, entropy, enthalpy and free energy change of the formed ion-associates were carried out. The drug concentration was also...

Two simple and high sensitive spectrophotometric methods have been developed for the quantitative determination of clopidogrel bisulfate (CLPB), in pure form and in pharmaceutical formulations, through H-point standard addition method (HPSAM) which showed suitable abilities to resolve accurately overlapped absorption spectra of the compounds by simultaneous determination of CLPB in its binary mixture with aspirin (ASP), and the other method is ion-pair formation reactions with some sulphonphthalein, e.g. bromophenol blue (BPB), bromocresol purple (BCP), bromocresol green (BCG), and...