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Studying of the neurobiology of Alzheimer's disease, this book reviews amyloid, the main molecular factor of neurodegeneration in this disease. It provides a synopsis of the information about ischemic cellular and molecular mediators involved in Alzheimer'

This new book presents a summary of Alzheimers disease-related ischemic protein changes and gene expression as risk factors for the late-onset of sporadic Alzheimers disease, and their role in Alzheimers disease ischemic etiology. Ischemic brain changes were noted in the staining of different parts of an amyloid protein precursor, presenilin 1 and 2, tau protein, alfa-synuclein, and apolipoproteins A1, E and J. Current advances in understanding the ischemic etiology of Alzheimers disease has revealed dysregulation of Alzheimers disease-associated genes including presenilin 1 and 2,...