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"Only a man who knows what it is like to be defeated can reach down to the bottom of his soul and come up with the extra ounce of power it takes to win when the match is even"- Muhammad Ali. Such were the words of the great boxing legend. In 1984, Ali was diagnosed with Parkinson's syndrome, a disease much more common in those subjected to severe head trauma, such as boxers. Ali began showing symptoms of the disease soon after retiring from the boxing ring in 1981. But his condition was not diagnosed until three years later. By that stage he had developed tremors, his speech was slurred, and...

The objective of the research work was to design novel proniosomes containing highly potent drug tretinoin. In this research work, proniosomes have been prepared by all the three known methods which are COACERVATION PHASE SEPARATION METHOD, SLURRY METHOD and third SLOW SPRAY COATING METHOD. In first method that is coacervation phase separation method the amount of cholesterol and phospholipids were kept constant but the different surfactants are used in varying ratios which has effect on drug entrapment, vesicle size and entrapment efficiency of prepared proniosomes. The proniosome...

The sugar substitutes discussed in this this book, which may also be called alternative, artificial, high-intensity, or non-nutritive sweeteners, can replace the sweetness of sugar while providing few or no calories. In addition to the calorie savings, these sugar substitutes have the advantage of not promoting tooth decay, and they are useful in dietary planning for people who are coping with obesity or diabetes. Each of these sugar substitutes is discussed individually. Sugar substitutes includes both food ingredients with very strong sweetening power that provide zero or very few calories,...