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In order to deal with issues that arise from the increase of biological data in genomic and proteomic research, broader coverage of recent developments in the field of knowledge-based systems and their applications is required. This book provides comprehensive coverage of knowledge-driven approaches to bioinformatics.

Written by Ron Alterovitz and Ken Goldberg, this monograph combines ideas from robotics, physically-based modeling, and operations research to develop new motion planning and optimization algorithms for image-guided medical procedures.