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Metal Ions in Biological Systems is devoted to increasing our understanding of the relationship between the chemistry of metals and life processes. The volumes reflect the interdisciplinary nature of bioinorganic chemistry and coordinate the efforts of researchers in the fields of biochemistry, inorganic chemistry, coordination chemistry, environmental chemistry, biophysics, pharmacy, and medicine.

Volume 43 focuses on the vibrant research area concerning the cycling of elements, metals, and non-metals in biology and geology; in 10 chapters this book offers an...

These sulfur-rich chelators, being important in metal ion homeostasis, find increasing attention. MILS-5, written by 30 internationally recognized experts, focuses on this hot topic. This book is an essential resource for scientists working in the wide range from environmental toxicology and inorganic biochemistry all the way through to physiology and medicine.

This book describes structural and catalytic roles of metal ions in RNA in an authoritative and timely manner. It deals with diffuse metal ion binding, RNA quadruplexes, the regulation of riboswitches, metal ions and ribozymes, including artificial ribozymes. The spliceosome, the ribosome, ribozymes involving redox cofactors as well as the binding of kinetically inert metal ions to RNA are also covered.

The occurrence of a wide variety of metal-carbon bonds in living organisms, ranging from bacteria to humans, is only recently appreciated. Of course, the historical examples are the B12 coenzymes containing cobalt-carbon bonds, but now such bonds are also known for nickel, iron, copper, and other transition metal ions. MILS-6, written by 20 experts, summarizes the most recent insights into this fascinating topic.

Organometallics in Environment and Toxicology highlights in an authoritative and timely manner environmental cycles of elements involving organometal(loid) compounds as well as the analytical determination of such species. This book examines methane formation involving the nickel coenzyme F430, as well as the organometal(loid) compounds formed by tin, lead, arsenic, antimony, bismuth, selenium, tellurium, and mercury.

MILS-8 deals with the risk assessment of toxic metal ions and their interdependencies focusing on humans and their organs; thus it carries on the topic of MILS-7 that centered on the environment. This book is of special relevance for researchers in toxicology, enzymology, health and safety institutions, those dealing with industrial safety regulations, and also for analytical, bioinorganic, and environmental chemists.

Volume 22, entitled Metal Ions in Bio-Imaging Techniques, of the series Metal Ions in Life Sciences deals with metal ions as tools in imaging. This dates back to the first half of the past century, when barium sulfate was orally given to patients undergoing X-ray examination. The use of contrast agents has since developed into a large interdisciplinary field encompassing not only medicine, but also chemistry, material sciences, physics, biology, engineering, and computer sciences. MILS-22 provides deep and current insights in 17 stimulating chapters on the new research frontiers of this fast...

MILS-16 provides an up-to-date review of the impact of alkali metal ions on life. This and more is treated in an authoritative and timely manner in the 16 stimulating chapters of Volume 16, The Alkali Metal Ions: Their Role for Life, which are written by 44 internationally recognized experts from 12 nations.

Volume 11 provides in an authoritative and timely manner in 16 stimulating chapters, written by 40 internationally recognized experts from 11 nations, and supported by more than 2600 references, 35 tables, and over 100 illustrations, many in color, a most up-to-date view on the role of cadmium for life, presently a vibrant research area.

MILS-16 provides an up-to-date review of the impact of alkali metal ions on life. Their bioinorganic chemistry and analytical determination, the solid state structures of bio-ligand complexes and the properties of alkali metal ions in solution in the context of all kinds of biologically relevant ligands are covered, this includes proteins (enzymes) and nucleic acids (G-quadruplexes). Minerals containing sodium (Na+) and potassium (K+) are abundant in the Earth's crust, making Na+ and K+ easily available. In contrast, the alkali elements lithium (Li+), rubidium, and cesium are rare and the...

Volume 11 provides in an authoritative and timely manner in 16 stimulating chapters, written by 40 internationally recognized experts from 11 nations, and supported by more than 2600 references, 35 tables, and over 100 illustrations, many in color, a most up-to-date view on the role of cadmium for life, presently a vibrant research area. MILS-11 covers the bioinorganic chemistry of Cd(II), its biogeochemistry, anthropogenic release into the environment, and speciation in the atmosphere, waters, soils, and sediments. The analytical tools for Cd determination, its imaging in cells, and the use...