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Clinical trials have become essential research tools for evaluating the benefits and risks of new interventions for the treatment and prevention of diseases, from cardiovascular disease to cancer to AIDS. Based on the authors collective experiences in this field, Introduction to Statistical Methods for Clinical Trials presents various statistical topics relevant to the design, monitoring, and analysis of a clinical trial.

After reviewing the history, ethics, protocol, and regulatory issues of clinical trials, the book provides guidelines for formulating primary and secondary...

Larisa Reisner (1895–1926), fighter, commissar, and diplomat, was one of the most brilliant and popular writers of the Russian Revolution. Her journalism from her travels in Russia and Ukraine, Germany, Persia and Afghanistan was read by millions in the new mass circulation Soviet press. Together here for the first time in translation are the six books of her journalism, The Front, Afghanistan, Berlin October 1923, Hamburg at the Barricades and In Hindenburg's Country, all written in the last nine years of her life, before her death at the age of thirty. This volume is published as the...