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Oral squamous cell carcinoma is the sixth most common malignancy and is a major cause of cancer morbidity and mortality worldwide. Recent discoveries have dramatically increased our understanding of the most basic mechanisms controlling normal cell growth, and have also greatly enhanced our ability to investigate the nature of the biological processes that lead to cancer. Mathematical models predict that 8-10 individual genetic aberrations are required for progression to head and neck cancer alongwith hundreds of genetic aberrations, the vast majority unrelated to their pathogenesis. The...

Gross pathology refers to the macroscopic manifestations of disease in organs, tissues, and body cavities. Grossing is a very important step in surgical pathology and inadequate sampling of the gross specimen can lead to misinterpretation of the slides. For oral and maxillofacial specimens, a careful gross examination and description are infinitely superior to the examination of a random microscopic section. This book provides a highly visual step by step guide to grossing procedure like inital handling of the specimen, from where to take sections, how to do reporting etc. Contains high...