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Computational models can be found everywhere in present day science and engineering. In providing a logical framework and foundation for the specification and design of specification languages, Raymond Turner uses this framework to introduce and study computable models. In doing so he presents the first systematic attempt to provide computational models with a logical foundation.

Computable models have wide-ranging applications from programming language semantics and specification languages, through to knowledge representation languages and formalism for natural language semantics....

It covers all aspects of DC generation, function, survival and antitumor activity in the tumor environment both in vivo and in experimental in vitro systems. The goal in focusing on a spectrum of issues related to DC in cancer is to provide an extensive and expansive review rather than a collection of independent analyses from different authors.

Specific topics to be covered include analysis of DC behavior in the tumor microenvironment, including endogenous and exogenous DC, multiple DC populations, molecular pathways responsible for DC dysfunction, tumor-derived factors altering DC...

The coupling of models from different physical domains and the efficient and reliable simulation of multidisciplinary problems in engineering applications are important topics for various fields of engineering, in simulation technology and in the development and analysis of numerical solvers.

The volume presents advanced modelling and simulation techniques for the dynamical analysis of coupled engineering systems consisting of mechanical, electrical, hydraulic and biological components as well as control devices often based on computer hardware and software. The book starts with...

Pain is a common symptom, yet it is frequently underevaluated and undertreated. It is difficult to define, describe and sometimes to prove. It s pain, and suspicions of exaggerations often add further insult to a patients injuries. Biobehavioral Approaches to Pain translates this highly subjective experience and its physical, psychological, social, and cultural dimensions into practical insights key to transforming the field of pain management.

This pathbreaking volume synthesizes a rich knowledge base from across disciplines, including neurobiologic, genetic,...

Apoptosis: Involvement of Oxidative Stress and Intracellular Ca²⁺ Homeostasis, presents a concise synthesis of the current knowledge and recent advances in the mechanisms of apoptosis in different cells and the role of oxidative stress and Ca²⁺ signalling. Particular attention is given to the different features of apoptosis in distinct cell types, ranging from hepatocytes to cardiovascular and blood cells, nervous cells or spermatozoa.

Cutting-edge and user-friendly, this volume serves as a comprehensive resource for those interested in the...

The geocomputational expression is related to the development and application of new theories, methods and tools in order to provide better solutions to complex geographical problems. This text covers new urban applications of geocomputational analysis.

The mechanisms of protest and revolution have been the subject of theoretical research for over a century, yet the lack of data has hindered the empirical validation of conflicting theories. In this book, the author presents a unique new set of sub-daily data from over thirty countries and seven civil wars and uses them to test two models of conflict, the predator-prey model and the competing species model. The dynamic nature of the data modelling and the novelty of the dataset make this work a unique contribution to the field of conflict research. Dynamics of Conflict will help to...

During the last two decades silicon-containing dendritic polymers have become one of the fastest growing areas of development in polymer science. The eruption of interest in these new polymers stems from their unprecedented molecular architecture, unique resulting properties and the realization that they represent ideal building blocks for chemical nanotechnology.

This is the first book to solely focus on silicon-containing dendritic polymers. The contributions of those experts who originally introduced each field or played a major role in its progress are reported. The developments...