Wyniki wyszukiwania:

In medicinal chemistry the chemist attempts to design and synthesize a medicine or a pharmaceutical agent which will benefit humanity. In the last century, the classical drugs were primarily discovered. Heterocyclic compounds represent an important class of biological active molecules. Specifically those containing quinoxaline derivatives have evoked considerable attention in recent years. They possess wide range of biological activities. Quinoxaline, also called a benzo-pyrazine, a ring complex made up of a benzene ring and a pyrazine ring. Numerous methods are available for the syntheses of...

The main goal of present study was to formulate and invitro evaluate bilayer tablets of Metoprolol tartrate and Hydrochlorothiazide. In this tablet hydrochlorothiazide was formulated as immediate release for which sodium starch glycolate and croscarmellose sodium was used as superdisintegrants. While metoprolol tartrate was formulated as sustained release for which HPMC K4 M and Eudragit RSPO were used as release retarding polymers. In this bilayer tablet hydrochlorothiazide showed quick action and the sustained release of metoprolol tartrate maintain the drug concentration within therapeutic...