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Niosomes was developed and characterized for ocular drug delivery of diclofenac potassium. The present research study is a promising approach to improve corneal penetration and bio availability characteristics. Formulation also found to ensure a good entrapment efficiency and ocular bio availability of drug in-vivo. Niosome containing diclofenac potassium were prepared using surfactant and cholesterol in different ratio by Lipid film hydration technique. Niosomes were characterized For Entrapment efficiency, Particle size analysis, In-vitro drug release and In-vivo studies. Formulation with...

This Particular Book Chapter includes all the aspects related to Freeze-Drying. Data shows how to characterize a crystalline matrix-type formulation to successfully develop a lyophilization cycle. We describe how to generate a water adsorption curve and conduct a moisture optimization. protein-formulation characterization studies are carried out with the all emphasis containing Lyophilization along with generated description of Freeze- Drying.