ISBN-13: 9786202051569 / Angielski / Miękka / 2017 / 84 str.
ISBN-13: 9786202051569 / Angielski / Miękka / 2017 / 84 str.
This book is focused on the development of newer non-steroidal anti-inflammatory agents (NSAIAS) which could establish as newer promising NSAIDS. Synthesis of new heterocycles viz. thiazoles, pyrazoles and 2, 4-thiazolidinone-diones possessing COX-2 selective methyl sulphonamide pharmacophore by rational drug design approach is reported. In vitro and in vivo anti-inflammatory screening data of synthesized compounds is recorded.