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"The Winter Slump - Surviving the psychological crash just past the halfway point" investigates the "Third Quarter Phenomenon." Research on polar explorers, submarine crews, and astronauts reveals a consistent pattern: Morale doesn't drop at the beginning or the end of a mission, but exactly in the third quarter. It is the moment when the novelty has faded, but the end is not yet in sight.Author Rachel Snow applies this finding to everyday life. Whether it is the middle of a project, a semester, or a pandemic, the third quarter is where humans are biologically programmed to become irritable,...

Pharmacokinetic variability of contraceptive steroids is a relatively under-explored area of contraceptive research, and hardly a common point of discussion among those who plan and deliver family planning services. Nevertheless, numerous independent studies over the last 15 years have indicated that women in different regions of the world vary in their pharmacokinetic response to contraceptive steroids. The causes of such variability are not known, but it has important consequences for contraceptive effectiveness. It may also offer insight to the basis of contraceptive side-effects. The...

Synthesizes the evidence collected over the past 15 years that women in different parts of the world react differently to contraceptive steroids, both in contraceptive effectiveness and in side effects, and explores possible causes and implications of the variation. Considers women's own experience