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'My thoughts on the spiritual exercises proper to cloistered monks'; the ninth prior of La Grande Chartreuse ( '1180) articulates the monastic contemplative tradition in distinctively western terms.

'...reading, meditation, prayer and contemplation. These make a ladder for monks by which they are lifted up from earth to heaven. It has few rungs, yet its length is immense and wonderful, for its lower end rests upon the earth, but its top pierces the clouds and seeks heavenly secrets.'

The fifth prior of the Grande Chartreuse, Guigo I was esteemed as 'a prior worthy of eternal fame', a prudent man and immensely erudite in both secular and sacred studies. His personal reflections on Holy Scripture take the form of a spiritual journey in which he blends theology and personal experience, daily practicality and ascetic insight, in a way both typical of twelfth-century reformed monasticism and uniquely carthusian.

We are pleased to present the proceedings of the Second Workshop on Al- rithms in Bioinformatics (WABI 2002), which took place on September 17-21, 2002 in Rome, Italy. The WABI workshop was part of a three-conference me- ing, which, in addition to WABI, included the ESA and APPROX 2002. The three conferences are jointly called ALGO 2002, and were hosted by the F- ulty of Engineering, University of Rome "La Sapienza." Seehttp: //www.dis. uniroma1.it/ algo02 for more details. The Workshop on Algorithms in Bioinformatics covers research in all areas of algorithmic work in bioinformatics and...

A collection of key texts from early Carthusian writing in the IIth and 12th Centuries. St Bruno: Letter to his Carthusian sons at the Chartreuse, The Letter to Raoul le Verd, Profession of Faith. Bl. Guigo, fifth prior of the Grande Chartreuse: Letter on the solitary life. Guigo II, ninth prior of the Grande Chartreuse: The scale of the cloister. Other books of classic Carthusian spirituality published by Gracewing include The Call of Silent Love, Interior Prayer, The Prayer of Love and Silence, They Speak by Silences, The Way of Silent Love and The Wound of Love.