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Black Pepper (Piper nigrum) is a wonderful spice with a rich history and many uses in the kitchen and in the medicine. In traditional medicine, black pepper has been used for digestive disorders, such as indigestion, vomiting, diarrhoea, and flatulence. Present study was carried out to investigate the antidiarrhoeal and antispasmodic effect and different mechanisms of antidiarrhoeal and antispasmodic action of black pepper. Antidiarrhoeal activity of black pepper was studied in mice in diarrhoea induced by castor oil model, magnesium sulphate induced diarrhoea model, Charcoal meal test for...

Diarrhoea is a frequent medical problem. Intestinal infection is the most common cause of diarrhoea worldwide and is responsible for the deaths of 3-4 million individuals each year, mostly in preschool-age children. Mebarid syrup, Enterocin syrup and Kutajarishta syrup are Ayurvedic antidiarrhoeal formulations. Though Mebarid, Enterocin and Kutajarishta are widely used in the treatment of diarrhoea and dysentery, still there is a paucity of data on the mechanisms of action of these formulations. Present study was aimed to investigate the anti-diarrhoeal effect and different mechanisms of...