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The research work was aimed to formulate a controlled porosity osmotic pump tablets of Diltiazem hydrochloride. The developed extended release formulation delivered a drug for 24 hr. Diltiazem hydrochloride having high solubility and relatively short half- life (3-4.5 hr.) suggest its suitability for an extended formulation. In this developed formulation pores are formed by the incorporation of a leachable component in the coating. Once the tablet comes in contact with the aqueous environment, Subsequently, water diffuses into the core through the microporous membrane, setting up an osmotic...