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Lung cancer has seen a paradigm shift in disease treatment over the past few years, with major changes in the therapeutic drugs now available as well as in the overall management approach.  For targeted and immunotherapeutic approaches, understanding the biology of acquired resistance is a key strategy that has yielded productive advances in the subsequent treatment.  Future advances also include incorporating biomarker data obtained from solid and liquid biopsies, as well as combination of immunotherapy with radiotherapy and in special populations such patients with CNS...

Key considerations for modeling in rates, equities and foreign exchange are presented from the perspective of common themes across various assets,...

The Monterey coast, home to an acclaimed aquarium and the setting for John Steinbeck's classic novel Cannery Row, was also the stage for a historical junction of industry and tourism. Shaping the Shoreline looks at the ways in which Monterey has formed, and been formed by, the tension between labor and leisure.

Connie Y. Chiang examines Monterey's development from a seaside resort into a working-class fishing town and, finally, into a tourist attraction again. Through the subjects of work, recreation, and environment -- the intersections of which are applicable to...

An important new resource for managers in marketing, finance, acquisitions analysis, and strategic planning, this book explores a question central to the financial health of every company: Is there a rate of corporate growth that is both desirable and sustainable? As the authors point out, excessive growth in sales can be as destructive to the survival of a firm as no growth. Here they present analytical models and tools that enable corporate planners to evaluate their own growth needs, target realistic expectations, and assess the collateral risks of growing either too fast or too slow....

This invaluable book systematically presents fundamental methods of statistical analysis: from basic probability and...

Organizations are swamped with data--collected from web traffic, point of sale systems, enterprise resource planning systems, and more, but what to do with it? Monetizing your Data provides a framework and path for business managers to convert ever-increasing volumes of data into revenue generating actions through three disciplines: decision architecture, data science, and guided analytics. There are large gaps between understanding a business problem and knowing which data is relevant to the problem and...