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The effort summarized preparation of N2O2 donor mixed ligand metal complexes containing biscoumarin with 1,10-phenanthroline (Ph). Structural and spectroscopic properties of neutral bidentate ligands as well as all complexes were studied on the basis of mass spectra, NMR (1H and 13C) spectra, FT-IR spectrum and elemental analyses. Mass spectral data confirm the structure of ligands as indicated by the molecular ion peak (M+) corresponding to their molecular weight. IR spectral data suggest tetra-coordinated N2O2 bonding of ligand toward metal ion. Furthermore, complexes investigated by means...

Efforts are done in the direction of searching the lead compound to discover new drugs in present research we synthesized different chalcone derivatives. with the advancement of science and technology, with the help of sophisticated instruments , we have successfully recapitulated our work in this book in the form of chapters and related analysis. we are please to represent our work in the field of organic chemistry that may be a path line for thousands of research scholars.

Interest in coumarin chemistry has flourished for many years; basically as a result of the wide spread use of coumarin derivatives. Coumarin, the basic molecule of the family of many derivatives, is the simplest naturally occurring phenolic substance possessing fused benzene and -pyrone rings. Naturally occurring as well as synthetic derivatives of coumarin compound are of importance in wide ranging fields as medicinal chemistry, biochemistry, plant science and pharmacology."

Kinetic studies have been reported for base catalyzed formation of chalcone and its derivatives. During the present century, chalcones and their derivatives have been observed to be much use. Thus, some chalcones exhibit therapeutic properties e.g. anticular activity, hypotensive activity etc. Antibiotic activity has been shown by some chalcones due to presence of an enone function. It has been observed that the bacteriostatic or bactericidal property gets increased with the introduction of a substituent like a nitro or bromo group at the position or a bromo or hydroxyl group at the...

The book focuses on the designing and development of transdermal drug delivery system for delivery of antihypertensive drugs. The transdermal route is a novel drug delivery aspect which mainly contributes towards patient compliance and sustained drug plasma level. Administration of drugs via dermal route can bypass various disadvantages caused when administered orally and may maintain relatively consistent plasma levels for long-term therapy. The book will prove to fruitful for researchers in the field of drug delivery.