wyszukanych pozycji: 7
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Fatty Acid and Lipotoxicity in Obesity and Diabetes
ISBN: 9780470057643 / Angielski / Twarda / 2008 / 222 str. Termin realizacji zamówienia: ok. 30 dni roboczych (Bez gwarancji dostawy przed świętami) The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic β cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose tissue. Maintaining the normal levels of fatty acids requires coordinated regulation between the liver, adipose tissue and skeletal muscle.
This book deals with the molecular aspects of fatty acid action in obesity and insulin resistance. The... The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin ...
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cena:
783,47 zł |
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Molecular Mechanisms Influencing Aggressive Behaviours
ISBN: 9780470010686 / Angielski / Twarda / 2005 / 272 str. Termin realizacji zamówienia: ok. 30 dni roboczych (Bez gwarancji dostawy przed świętami) This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular reference to possible implications for understanding human aggression. Chapters focus on the major current experimental issues in the study of aggression in humans and animals. The extensive discussions deal with specific problems of interpretation at the molecular level, as well as general issues relating to our understanding of human and animal aggression.
This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular referenc...
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cena:
809,34 zł |
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Osteoarthritic Joint Pain
ISBN: 9780470867617 / Angielski / Twarda / 2004 / 304 str. Termin realizacji zamówienia: ok. 30 dni roboczych (Bez gwarancji dostawy przed świętami) Osteoarthritis is a chronic degenerative disease associated with joint pain and loss of joint function. It has an estimated incidence of 4 out of every 100 people and significantly reduces the quality of life in affected individuals. The major symptoms are chronic pain, swelling and stiffness; severe, chronic joint pain is often the central factor that causes patients to seek medical attention. Within the affected joint, there is focal degradation and remodelling of articular cartilage, new bone formation (osteophytes) and mild synovitis.
Several mechanisms are thought to contribute to... Osteoarthritis is a chronic degenerative disease associated with joint pain and loss of joint function. It has an estimated incidence of 4 out of ever...
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cena:
809,34 zł |
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Defining Optimal Immunotherapies for Type 1 Diabetes
ISBN: 9780470723258 / Angielski / Twarda / 2008 / 222 str. Termin realizacji zamówienia: ok. 30 dni roboczych (Bez gwarancji dostawy przed świętami)
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cena:
768,87 zł |
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The Biology of Extracellular Molecular Chaperones
ISBN: 9780470723333 / Angielski / Twarda / 2008 / 248 str. Termin realizacji zamówienia: ok. 30 dni roboczych (Bez gwarancji dostawy przed świętami) The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of novel proteins within stressed cells, and the key signal stimulating this appearance was identified as the presence of unfolded proteins within the cell. It is now known that this is a key mechanism enabling cells to survive a multitude of physical, chemical and biological stresses.
Since the promulgation of the 'molecular chaperone' concept as a general cellular function to control the process of correct protein folding, a large number... The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearan...
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cena:
809,34 zł |
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The Molecular Basis of Skeletogenesis
ISBN: 9780471494331 / Angielski / Twarda / 2001 / 304 str. Termin realizacji zamówienia: ok. 30 dni roboczych (Bez gwarancji dostawy przed świętami) Brings together a cross-fertilization of ideas between human molecular genetics, develeopmental biology, tissue biology and the biochemistry of cell signalling pathways, in order to create new insights into the mechanisms of normal and abnormal skeletogenesis.
Brings together a cross-fertilization of ideas between human molecular genetics, develeopmental biology, tissue biology and the biochemistry of cell s...
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cena:
809,34 zł |
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The Genetics and Biology of Sex Determination
ISBN: 9780470843468 / Angielski / Twarda / 2005 / 280 str. Termin realizacji zamówienia: ok. 30 dni roboczych (Bez gwarancji dostawy przed świętami) Nature employs a wide variety of sex determining mechanisms and it is only comparatively recently that the tools have become available for these to be explored at the cellular and molecular levels. A major landmark was the discovery in 1990 of the SRY gene and the subsequent demonstration of its key role in triggering male sex determination in transgenic mice.
This book reviews and discusses our current understanding of the molecular genetic pathways of sex determination, with special emphasis on vertebrates. It features comparisons with other modes of sex determination,... Nature employs a wide variety of sex determining mechanisms and it is only comparatively recently that the tools have become available for these to be...
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cena:
809,34 zł |