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wyszukanych pozycji: 11
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Fatty Acid and Lipotoxicity in Obesity and Diabetes
ISBN: 9780470057643 / Angielski / Twarda / 2008 / 222 str. Termin realizacji zamówienia: ok. 22 dni roboczych. The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic β cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose tissue. Maintaining the normal levels of fatty acids requires coordinated regulation between the liver, adipose tissue and skeletal muscle.
This book deals with the molecular aspects of fatty acid action in obesity and insulin resistance. The... The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin ...
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cena:
878,79 zł |
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Molecular Mechanisms Influencing Aggressive Behaviours
ISBN: 9780470010686 / Angielski / Twarda / 2005 / 272 str. Termin realizacji zamówienia: ok. 22 dni roboczych. This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular reference to possible implications for understanding human aggression. Chapters focus on the major current experimental issues in the study of aggression in humans and animals. The extensive discussions deal with specific problems of interpretation at the molecular level, as well as general issues relating to our understanding of human and animal aggression.
This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular referenc...
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cena:
862,41 zł |
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Empathy and Fairness
ISBN: 9780470026267 / Angielski / Twarda / 2006 / 240 str. Termin realizacji zamówienia: ok. 22 dni roboczych. This book brings together work from a wide range of disciplines to explain processes underlying empathy and fairness. It approaches the topic of empathy and fairness from different viewpoints, namely those of social cognitive neuroscience, developmental psychology, evolutionary anthropology, economics, and neuropathology.
This book brings together work from a wide range of disciplines to explain processes underlying empathy and fairness. It approaches the topic of empat...
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cena:
878,79 zł |
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Role of the Sarcoplasmic Reticulum in Smooth Muscle
ISBN: 9780470844793 / Angielski / Twarda / 2002 / 296 str. Termin realizacji zamówienia: ok. 22 dni roboczych. Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to serious pathological conditions, such as hypertension and pre-term labour. The calcium ion plays a central role in smooth muscle function, increasing in concentration for contraction and decreasing for relaxation. Calcium entry into the cell is facilitated by the sarcoplasmic reticulum (SR).
This book explores the latest research on the role of the sarcoplasmic reticulum (SR) in smooth muscle function. It examines the control and modulation of... Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to s...
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cena:
862,41 zł |
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Osteoarthritic Joint Pain
ISBN: 9780470867617 / Angielski / Twarda / 2004 / 304 str. Termin realizacji zamówienia: ok. 22 dni roboczych. Osteoarthritis is a chronic degenerative disease associated with joint pain and loss of joint function. It has an estimated incidence of 4 out of every 100 people and significantly reduces the quality of life in affected individuals. The major symptoms are chronic pain, swelling and stiffness; severe, chronic joint pain is often the central factor that causes patients to seek medical attention. Within the affected joint, there is focal degradation and remodelling of articular cartilage, new bone formation (osteophytes) and mild synovitis.
Several mechanisms are thought to contribute to... Osteoarthritis is a chronic degenerative disease associated with joint pain and loss of joint function. It has an estimated incidence of 4 out of ever...
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cena:
862,41 zł |
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Defining Optimal Immunotherapies for Type 1 Diabetes
ISBN: 9780470723258 / Angielski / Twarda / 2008 / 222 str. Termin realizacji zamówienia: ok. 22 dni roboczych.
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cena:
862,41 zł |
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The Biology of Extracellular Molecular Chaperones
ISBN: 9780470723333 / Angielski / Twarda / 2008 / 248 str. Termin realizacji zamówienia: ok. 22 dni roboczych. The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of novel proteins within stressed cells, and the key signal stimulating this appearance was identified as the presence of unfolded proteins within the cell. It is now known that this is a key mechanism enabling cells to survive a multitude of physical, chemical and biological stresses.
Since the promulgation of the 'molecular chaperone' concept as a general cellular function to control the process of correct protein folding, a large number... The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearan...
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cena:
862,41 zł |
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Mechanisms and Biological Significance of Pulsatile Hormone Secretion
ISBN: 9780471999188 / Angielski / Twarda / 2000 / 280 str. Termin realizacji zamówienia: ok. 22 dni roboczych. This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the induction of biological responses. Coverage includes the basic mechanisms involved in hormone pulsatility, the significance of pulsatility in normal and disease conditions, the relevance of circadian rhythms, changes with ageing, and detailed consideration of specific peptide hormone systems. This book includes contributions from professionals working in both basic and clinical research and reveals much new and exciting work in this area and...
This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the in...
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cena:
862,41 zł |
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The Molecular Basis of Skeletogenesis
ISBN: 9780471494331 / Angielski / Twarda / 2001 / 304 str. Termin realizacji zamówienia: ok. 22 dni roboczych. Brings together a cross-fertilization of ideas between human molecular genetics, develeopmental biology, tissue biology and the biochemistry of cell signalling pathways, in order to create new insights into the mechanisms of normal and abnormal skeletogenesis.
Brings together a cross-fertilization of ideas between human molecular genetics, develeopmental biology, tissue biology and the biochemistry of cell s...
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cena:
862,41 zł |
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Sodium Channels and Neuronal Hyperexcitability
ISBN: 9780471485308 / Angielski / Twarda / 2001 / 248 str. Termin realizacji zamówienia: ok. 22 dni roboczych. Recent progress has led to a better understanding of the molecular structure of sodium channels, how they work and the mechanisms that restrict their expression to particular cell types.
This book explains how these channels are modulated in various pathological states to enable the development of therapeutic strategies based on sodium channel restoration. The authors present the most current research on sodium channels and neuronal function.
Recent progress has led to a better understanding of the molecular structure of sodium channels, how they work and the mechanisms that restrict their ...
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cena:
862,41 zł |
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The Genetics and Biology of Sex Determination
ISBN: 9780470843468 / Angielski / Twarda / 2005 / 280 str. Termin realizacji zamówienia: ok. 22 dni roboczych. Nature employs a wide variety of sex determining mechanisms and it is only comparatively recently that the tools have become available for these to be explored at the cellular and molecular levels. A major landmark was the discovery in 1990 of the SRY gene and the subsequent demonstration of its key role in triggering male sex determination in transgenic mice.
This book reviews and discusses our current understanding of the molecular genetic pathways of sex determination, with special emphasis on vertebrates. It features comparisons with other modes of sex determination,... Nature employs a wide variety of sex determining mechanisms and it is only comparatively recently that the tools have become available for these to be...
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cena:
862,41 zł |
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