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Ointments are made from animal, minerals & plant extracts that were widely utilized in Egyptian & Babylonian healthcare in 3000BC. The skin, vagina, eye, and nose are the principal routes for topical delivery that have been extensively studied. The present research was based on formulation and evaluation of Nanogel of Etodolac for topical action in Rheumatoid Arthritis. Nanogel was prepared using standard procedure then was evaluated using various parameters i.e., pH, % drug content, Physical appearance, Droplet size & Polydispersity index (PDI), In-vitro drug release, Viscosity, Stability...