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The main goals of this paper are: (i) To develop an abstract differential calculus on metric measure spaces by investigating the duality relations between differentials and gradients of Sobolev functions. This will be achieved without calling into play any sort of analysis in charts, our assumptions being: the metric space is complete and separable and the measure is Radon and non-negative. (ii) To employ these notions of calculus to provide, via integration by parts, a general definition of distributional Laplacian, thus giving a meaning to an expression like $Delta g=mu$, where $g$ is a...

The author discusses in which sense general metric measure spaces possess a first order differential structure. Building on this, spaces with Ricci curvature bounded from below a second order calculus can be developed, permitting the author to define Hessian, covariant/exterior derivatives and Ricci curvature.