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Studies on the prevalence of the Extended Spectrum Beta Lactamase Enzyme Producing Enterobacteriaceae Group of Bacterial isolates from Bovine Milk were undertaken in the 100 samples, giving a prevalence rate of 14%. Three standard methods used were Combine disc diffusion test (CDDT), Double disc synergy test (DDST), and Enzyme MIC strip method. Among the three methods CDDT method showed maximum sensitivity, and the Ezy MIC strip method was found to be least sensitive. Multi-drug resistant profiles of ESBL-positive isolates were also observed against Amikacin, Cefuroxime, Cefixime, Ampicillin...

Antimicrobial resistance has become a burning issue in humans and animals. Extended-spectrum beta-lactamase is produced by certain bacteria which has the capacity to inhibit the effect of third-generation cephalosporins and beta-lactam antibiotics. E coli being an indicator organism if it produces extended-spectrum beta-lactamase enzyme in healthy broilers it could be very alarming. The present study was conducted on caecal samples collected from freshly slaughtered healthy broilers, characterized both phenotypically and genotypically. The beta lactamase enzyme obtained was studied for the...