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This book presents an in-depth exploration of the molecular mechanisms underlying neuronal survival and repair after ischemic brain injury. Focusing on the purinergic P2X4 receptor, the book examines how selective small-molecule modulators can influence neuroinflammation, synaptic plasticity, and vascular remodeling in stroke recovery. It integrates experimental findings, pharmacological strategies, and translational perspectives to bridge basic neuroscience with clinical neurotherapeutics. Readers gain a comprehensive understanding of P2X4-mediated signaling pathways, neuroimmune...