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The present investigation comprises a survey covering the antioxidant activities of compounds containing the oxadiazole, thiadiazole and triazole ring system, with particular reference to benzimidazole and indole derivatives. In this work, 34 intermediates and 128 new compounds derived from indole and benzimidazole were synthesized. The structures of new compounds were confirmed by both analytical and spectral data (IR, NMR and MS). The antioxidant activities were tested in vitro using DPPH radical scavenging assay.

The present investigation comprises a survey covering the biological activities of compounds containing the indole ring system, with particular reference to indole-2-carboxylate and pyridazinoindole derivatives. The Microwave assistance of selected reactions has profouned effect on the speed of reactions. The structures of new compounds were confirmed by both analytical and spectral data. substituted indolylthiazolidinones were evaluated for their anticonvulsant as well as tranquilizing activities. The results show that, all tested compounds protected significantly against the strychnine...